ID 1.21.3.7 DE tetrahydrocannabinolic acid synthase. AN Delta(1)-tetrahydrocannabinolic acid synthase. AN THCA synthase. CA cannabigerolate + O2 = Delta(9)-tetrahydrocannabinolate + H2O2. CC -!- The cofactor is covalently bound. CC -!- Part of the cannabinoids biosynthetic pathway in the plant Cannabis CC sativa. CC -!- The enzyme can also convert cannabinerolate (the (Z)-isomer of CC cannabigerolate) to Delta(9)-THCA with lower efficiency. CC -!- The traditional numbering called Delta(9)-tetrahydrocannabinolate, CC Delta(1)-tetrahydrocannabinolate. CC -!- Systematic peripheral numbering is now recommended. DR Q8GTB6, THCAS_CANSA; //