ENZYME entry: EC 1.21.4.1

Accepted Name
D-proline reductase (dithiol).
Reaction catalysed
5-aminopentanoate + lipoate <=> D-proline + dihydrolipoate
Cofactor(s)
Pyruvate.
Comment(s)
  • The reaction is observed only in the direction of D-proline reduction.
  • Other dithiols can function as reducing agents; the enzyme contains a pyruvoyl group and a selenocysteine residue, both essential for activity.
  • Formerly EC 1.4.1.6 and EC 1.4.4.1.
Cross-references
BRENDA1.21.4.1
EC2PDB1.21.4.1
ExplorEnz1.21.4.1
PRIAM enzyme-specific profiles1.21.4.1
KEGG Ligand Database for Enzyme Nomenclature1.21.4.1
IUBMB Enzyme Nomenclature1.21.4.1
IntEnz1.21.4.1
MEDLINEFind literature relating to 1.21.4.1
MetaCyc1.21.4.1
UniProtKB/Swiss-Prot
Q9Z4P6, PRDA_CLOSD;  Q9Z4Q7, PRDB_CLOSD;  

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