ID   1.21.4.3
DE   Sarcosine reductase.
CA   Acetyl phosphate + methylamine + thioredoxin disulfide + H(2)O =
CA   N-methylglycine + phosphate + thioredoxin.
CC   -!- The reaction is observed only in the direction of sarcosine
CC       reduction.
CC   -!- The enzyme from Eubacterium acidaminophilum consists of subunits A,
CC       B and C.
CC   -!- Subunit B contains selenocysteine and a pyruvoyl group, and is
CC       responsible for sarcosine binding and methylamine release.
CC   -!- Subunit A, which also contains selenocysteine, is reduced by
CC       thioredoxin, and is needed to convert the carboxymethyl group into a
CC       ketene equivalent, in turn used by subunit C to produce acetyl
CC       phosphate.
CC   -!- Only subunit B distinguishes this enzyme from EC 1.21.4.2 and
CC       EC 1.21.4.4.
DR   P50972, GRDA1_EUBAC;  Q6LH20, GRDA1_PHOPR;  O32518, GRDA2_EUBAC;
DR   Q6LH19, GRDA2_PHOPR;  A6TU46, GRDA_ALKMQ ;  Q3A9J5, GRDA_CARHZ ;
DR   A7FTE0, GRDA_CLOB1 ;  A7GCV1, GRDA_CLOBL ;  P52216, GRDA_CLOLI ;
DR   P26970, GRDA_CLOPU ;  P26971, GRDA_CLOSD ;  Q67KE6, GRDA_SYMTH ;
DR   Q73PQ2, GRDA_TREDE ;  P54935, GRDC_EUBAC ;  Q47878, GRDD_EUBAC ;
DR   O86186, GRDF_EUBAC ;  O86185, GRDG_EUBAC ;
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