Expasy logo

ENZYME

ENZYME entry: EC 1.21.99.5

Accepted Name
tetrachloroethene reductive dehalogenase
Alternative Name(s)
tetrachloroethene reductase
Reaction catalysed
A + chloride + H(+) + trichloroethene <=> AH2 + tetrachloroethene
Comment(s)
  • This enzyme allows the common pollutant tetrachloroethene to support bacterial growth and is responsible for disposal of a number of chlorinated hydrocarbons by this organism.
  • The reaction occurs in the reverse direction.
  • The enzyme also reduces trichloroethene to dichloroethene.
  • Although the physiological reductant is unknown, the supply of reductant in some organisms is via reduced menaquinone, itself formed from molecular hydrogen, via EC 1.12.5.1.
  • Methylviologen can act as electron donor.
  • Formerly EC 1.97.1.8.
Cross-references
BRENDA1.21.99.5
EC2PDB1.21.99.5
ExplorEnz1.21.99.5
PRIAM enzyme-specific profiles1.21.99.5
KEGG Ligand Database for Enzyme Nomenclature1.21.99.5
IUBMB Enzyme Nomenclature1.21.99.5
IntEnz1.21.99.5
MEDLINEFind literature relating to 1.21.99.5
MetaCyc1.21.99.5
Rhea expert-curated reactions1.21.99.5
UniProtKB/Swiss-Prot
Q8GJ31, PCEA2_DESHAQ8GJ27, PCEA_DEHRPQ848J2, PCEA_DESHA
Q8L172, PCEA_DESHYO68252, PCEA_SULMU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-