ENZYME entry: EC 1.22.1.1
| Accepted Name |
|---|
| Iodotyrosine deiodinase.
|
| Alternative Name(s) |
|---|
| Iodotyrosine dehalogenase 1. |
| Reaction catalysed |
|---|
| L-tyrosine + 2 NADP(+) + 2 I(-) <=> 3,5-diiodo-L-tyrosine + 2 NADPH |
| Cofactor(s) |
|---|
| FMN.
|
| Comment(s) |
|---|
- The enzyme activity has only been demonstrated in the direction of
3-deiodination.
- Present in a transmembrane flavoprotein.
|
| Cross-references |
|---|
| BRENDA | 1.22.1.1 |
| EC2PDB | 1.22.1.1 |
| ExplorEnz | 1.22.1.1 |
| PRIAM enzyme-specific profiles | 1.22.1.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.22.1.1 |
| IUBMB Enzyme Nomenclature | 1.22.1.1 |
| IntEnz | 1.22.1.1 |
| MEDLINE | Find literature relating to 1.22.1.1 |
| MetaCyc | 1.22.1.1 |
| UniProtKB/Swiss-Prot |
|
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