ID 1.3.1.101 DE 2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase [NAD(P)H]. AN 2,3-digeranylgeranylglycerophospholipid reductase. AN DGGGPL reductase. AN digeranylgeranylglycerophospholipid reductase. CA (1) 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NADP(+) = 2,3-bis-O- CA (geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADPH. CA (2) 2,3-bis-O-(phytanyl)-sn-glycerol 1-phosphate + 8 NAD(+) = 2,3-bis-O- CA (geranylgeranyl)-sn-glycerol 1-phosphate + 8 H(+) + 8 NADH. CC -!- The enzyme from the archaeon Thermoplasma acidophilum is involved in CC the biosynthesis of membrane lipids. CC -!- In vivo the reaction occurs in the reverse direction with the CC formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate. cf. CC EC 1.3.7.11. DR Q6L0M1, GGR_PICTO ; Q9HKS9, GGR_THEAC ; Q979Y7, GGR_THEVO ; //