ID 1.3.1.106 DE cobalt-precorrin-6A reductase. CA Co-precorrin-6B + NAD(+) = Co-precorrin-6A + H(+) + NADH. CC -!- The enzyme, which participates in the anaerobic (early cobalt CC insertion) pathway of adenosylcobalamin biosynthesis, catalyzes the CC reduction of the double bond between C-18 and C-19 of cobalt- CC precorrin-6A. CC -!- The enzyme from the bacterium Bacillus megaterium has no activity CC with NADPH. CC -!- See EC 1.3.1.54 for the corresponding enzyme that participates in the CC aerobic cobalamin biosynthesis pathway. DR Q57972, CBIJ_METJA ; Q977V1, CBIJ_METMI ; O27083, CBIJ_METTH ; DR O87691, CBIJ_PRIMG ; Q05591, CBIJ_SALTY ; P72711, CBIJ_SYNY3 ; //