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ENZYME

ENZYME entry: EC 1.3.1.116

Accepted Name
7beta-hydroxy-3-oxochol-24-oyl-CoA 4-desaturase
Reaction catalysed
7beta-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) <=> 7beta-hydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH
Comment(s)
  • The enzyme, characterized from the bacterium Clostridium scindens, participates in the bile acid 7alpha-dehydroxylation pathway.
  • The enzyme catalyzes the stereo-specific oxidation of its substrate and has no activity with the 7alpha anomer. cf. EC 1.3.1.115.
Cross-references
BRENDA1.3.1.116
EC2PDB1.3.1.116
ExplorEnz1.3.1.116
PRIAM enzyme-specific profiles1.3.1.116
KEGG Ligand Database for Enzyme Nomenclature1.3.1.116
IUBMB Enzyme Nomenclature1.3.1.116
IntEnz1.3.1.116
MEDLINEFind literature relating to 1.3.1.116
MetaCyc1.3.1.116
Rhea expert-curated reactions1.3.1.116
UniProtKB/Swiss-Prot
P32370, BAIH_CLOSV

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