Expasy logo

ENZYME

ENZYME entry: EC 1.3.1.77

PURL: https://purl.expasy.org/enzyme/EC/1.3.1.77
Accepted Name
anthocyanidin reductase [(2R,3R)-flavan-3-ol-forming]
Alternative Name(s)
ANR
anthocyanidin reductase
Reaction catalysed
  • a (2R,3R)-flavan-3-ol + 2 NAD(+) = an anthocyanidin with a 3-hydroxy group + 2 NADH + 2 H(+)
  • a (2R,3R)-flavan-3-ol + 2 NADP(+) = an anthocyanidin with a 3-hydroxy group + 2 NADPH + 2 H(+)
Comment(s)
  • The enzyme participates in the flavonoid biosynthesis pathway found in plants.
  • It catalyzes the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins.
  • While the enzyme from the legume Medicago truncatula can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana uses only NADPH.
  • Also, while the substrate preference of the M. truncatula is cyanidin>pelargonidin>delphinidin, the reverse preference is found with the Arabidopsis enzyme. cf. EC 1.3.1.112.
Cross-references
Rhea expert-curated reactions1.3.1.77
ExplorEnz1.3.1.77
IUBMB Enzyme Nomenclature1.3.1.77
UniProtKB/Swiss-Prot
Q9SEV0, BAN_ARATH
BRENDA1.3.1.77
MetaCyc1.3.1.77
KEGG Ligand Database for Enzyme Nomenclature1.3.1.77
EC2PDB1.3.1.77
MEDLINEFind literature relating to 1.3.1.77

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-