ENZYME entry: EC 1.3.1.9

Accepted Name
Enoyl-[acyl-carrier-protein] reductase (NADH).
Alternative Name(s)
Enoyl-ACP reductase.
NADH-enoyl acyl carrier protein reductase.
NADH-specific enoyl-ACP reductase.
Reaction catalysed
An acyl-[acyl-carrier protein] + NAD(+) <=> a trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH
Comment(s)
  • The enzyme catalyzes an essential step in fatty acid biosynthesis, the reduction of the 2,3-double bond in enoyl-acyl-[acyl-carrier- protein] derivatives of the elongating fatty acid moiety.
  • The enzyme from the bacterium Escherichia coli accepts substrates with carbon chain length from 4 to 18.
  • The enzyme from the bacterium Mycobacterium tuberculosis prefers substrates with carbon chain length from 12 to 24 carbons.
Cross-references
BRENDA1.3.1.9
EC2PDB1.3.1.9
ExplorEnz1.3.1.9
PRIAM enzyme-specific profiles1.3.1.9
KEGG Ligand Database for Enzyme Nomenclature1.3.1.9
IUBMB Enzyme Nomenclature1.3.1.9
IntEnz1.3.1.9
MEDLINEFind literature relating to 1.3.1.9
MetaCyc1.3.1.9
UniProtKB/Swiss-Prot
Q6Z0I4, FABI1_ORYSJ;  P58380, FABI1_RHIME;  Q6H5J0, FABI2_ORYSJ;  
P58381, FABI2_RHIME;  O67505, FABI_AQUAE;  Q9SLA8, FABI_ARATH;  
Q81GI3, FABI_BACCR;  P54616, FABI_BACSU;  P80030, FABI_BRANA;  
P57353, FABI_BUCAI;  Q8K9Q6, FABI_BUCAP;  Q89AM1, FABI_BUCBP;  
P0AEK5, FABI_ECO57;  P0AEK4, FABI_ECOLI;  Q820V5, FABI_ENTFA;  
P44432, FABI_HAEIN;  Q9ZMN7, FABI_HELPJ;  O24990, FABI_HELPY;  
Q9K151, FABI_NEIMB;  Q05069, FABI_NOSS1;  Q9ZFE4, FABI_PSEAE;  
Q9X450, FABI_RHIML;  Q1RH28, FABI_RICBR;  Q92IC6, FABI_RICCN;  
Q4ULZ7, FABI_RICFE;  Q9ZDG4, FABI_RICPR;  Q68X10, FABI_RICTY;  
P16657, FABI_SALTY;  P0AEK6, FABI_SHIFL;  P73016, FABI_SYNY3;  
Q6LPG9, FABV1_PHOPR;  Q9KRA3, FABV1_VIBCH;  Q87QB9, FABV1_VIBPA;  
Q8D8Y6, FABV1_VIBVU;  Q7MLJ0, FABV1_VIBVY;  Q6LP67, FABV2_PHOPR;  
Q9KLG0, FABV2_VIBCH;  Q87HT6, FABV2_VIBPA;  Q8D795, FABV2_VIBVU;  
Q7ME99, FABV2_VIBVY;  A4SLJ1, FABV_AERS4;  B6EHQ2, FABV_ALISL;  
B1Z1S8, FABV_BURA4;  Q1BJC5, FABV_BURCA;  B1K4I6, FABV_BURCC;  
A0B3G1, FABV_BURCH;  B4EKD5, FABV_BURCJ;  Q0B677, FABV_BURCM;  
Q39B48, FABV_BURL3;  A9ALQ1, FABV_BURM1;  A3MJ23, FABV_BURM7;  
A2S3E6, FABV_BURM9;  Q62L02, FABV_BURMA;  A1V3D9, FABV_BURMS;  
A3NU97, FABV_BURP0;  Q3JT99, FABV_BURP1;  A3N8J6, FABV_BURP6;  
B2T4A8, FABV_BURPP;  Q63TE9, FABV_BURPS;  Q2SV62, FABV_BURTA;  
A4JK23, FABV_BURVG;  Q13YR8, FABV_BURXL;  Q1QTN9, FABV_CHRSD;  
Q488Q1, FABV_COLP3;  B6J5G0, FABV_COXB1;  B6J235, FABV_COXB2;  
A9KD01, FABV_COXBN;  A9NB02, FABV_COXBR;  Q83EP5, FABV_COXBU;  
Q11W68, FABV_CYTH3;  C5BFN7, FABV_EDWI9;  B2VET7, FABV_ERWT9;  
A5FE91, FABV_FLAJ1;  A6H0N4, FABV_FLAPJ;  Q5QYR6, FABV_IDILO;  
A6VZ98, FABV_MARMS;  Q1H0P3, FABV_METFK;  B1ZZ93, FABV_OPITP;  
Q15YQ7, FABV_PSEA6;  A6V3E8, FABV_PSEA7;  B7V2Z1, FABV_PSEA8;  
Q02PB3, FABV_PSEAB;  Q9HZP8, FABV_PSEAE;  Q4KBE3, FABV_PSEF5;  
C3K5J5, FABV_PSEFS;  Q3IHQ9, FABV_PSEHT;  A5W907, FABV_PSEP1;  
B0KGW2, FABV_PSEPG;  Q88E33, FABV_PSEPK;  B1J2V6, FABV_PSEPW;  
A1SSJ9, FABV_PSYIN;  Q21HE4, FABV_SACD2;  A8GD62, FABV_SERP5;  
A1S4Y1, FABV_SHEAM;  B8E5E3, FABV_SHEB2;  A3D311, FABV_SHEB5;  
A6WLQ7, FABV_SHEB8;  A9KWI3, FABV_SHEB9;  Q12LA9, FABV_SHEDO;  
Q07ZY9, FABV_SHEFN;  A3QFX1, FABV_SHELP;  Q8EG14, FABV_SHEON;  
A8H609, FABV_SHEPA;  A4Y5I7, FABV_SHEPC;  B8CRF2, FABV_SHEPW;  
A1RL84, FABV_SHESW;  B1KLT1, FABV_SHEWM;  Q93HE4, FABV_STRAW;  
C5BQC9, FABV_TERTT;  C4LB77, FABV_TOLAT;  C5CWP4, FABV_VARPS;  
A5EZM5, FABV_VIBC3;  Q5E6G3, FABV_VIBF1;  B5FCI7, FABV_VIBFM;  
Q8PR25, FABV_XANAC;  Q3BZG2, FABV_XANC5;  Q4V0G3, FABV_XANC8;  
Q8PE66, FABV_XANCP;  Q2P9J6, FABV_XANOM;  B2SUY7, FABV_XANOP;  
Q9PCE6, FABV_XYLFA;  Q87CN3, FABV_XYLFT;  A1JT88, FABV_YERE8;  
A7FPC3, FABV_YERP3;  Q1C0B2, FABV_YERPA;  B2K867, FABV_YERPB;  
Q8Z9U1, FABV_YERPE;  A9R5S2, FABV_YERPG;  Q1CCJ2, FABV_YERPN;  
A4TSK9, FABV_YERPP;  Q663S5, FABV_YERPS;  B1JRQ0, FABV_YERPY;  
P34731, FAS1_CANAX;  Q9UUG0, FAS1_SCHPO;  P34229, FAS1_YARLI;  
P07149, FAS1_YEAST;  O07400, INHA_MYCAV;  P0A5Y7, INHA_MYCBO;  
P42829, INHA_MYCS2;  P9WGR0, INHA_MYCTO;  P9WGR1, INHA_MYCTU;  
Q92215, TOXC_COCCA;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-