ENZYME entry: EC 1.3.1.94

Accepted Name
Polyprenol reductase.
Reaction catalysed
Ditrans,polycis-dolichol + NADP(+) <=> ditrans,polycis-polyprenol + NADPH
Comment(s)
  • The reaction occurs in the reverse direction with reduction of the terminal double bond next to the alcohol group.
  • Isolated from human fetal brain tissue but present in all eukaryotes.
  • In mammalian cells dolichols are predominantly 18-21 isoprene units in length.
Cross-references
BRENDA1.3.1.94
EC2PDB1.3.1.94
ExplorEnz1.3.1.94
PRIAM enzyme-specific profiles1.3.1.94
KEGG Ligand Database for Enzyme Nomenclature1.3.1.94
IUBMB Enzyme Nomenclature1.3.1.94
IntEnz1.3.1.94
MEDLINEFind literature relating to 1.3.1.94
MetaCyc1.3.1.94
UniProtKB/Swiss-Prot
P40526, DFG10_YEAST;  Q9CAH5, POED1_ARATH;  A2XWN6, POED1_ORYSI;  
Q7XUH5, POED1_ORYSJ;  Q9SI62, POED2_ARATH;  B8B6G5, POED2_ORYSI;  
Q7F0Q2, POED2_ORYSJ;  D2HBV9, PORED_AILME;  A8X8R3, PORED_CAEBR;  
Q17428, PORED_CAEEL;  Q5RIU9, PORED_DANRE;  Q9VLP9, PORED_DROME;  
Q9H8P0, PORED_HUMAN;  C7T2J9, PORED_MESAU;  Q9WUP4, PORED_MOUSE;  
Q5RJM1, PORED_RAT;  Q8AVI9, PORED_XENLA;  Q0P4J9, PORED_XENTR;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
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