ENZYME entry: EC 1.3.1.94
| Accepted Name |
|---|
| Polyprenol reductase.
|
| Reaction catalysed |
|---|
| Ditrans,polycis-dolichol + NADP(+) <=> ditrans,polycis-polyprenol + NADPH |
| Comment(s) |
|---|
- The reaction occurs in the reverse direction with reduction of the
terminal double bond next to the alcohol group.
- Isolated from human fetal brain tissue but present in all eukaryotes.
- In mammalian cells dolichols are predominantly 18-21 isoprene units
in length.
|
| Cross-references |
|---|
| BRENDA | 1.3.1.94 |
| EC2PDB | 1.3.1.94 |
| ExplorEnz | 1.3.1.94 |
| PRIAM enzyme-specific profiles | 1.3.1.94 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.94 |
| IUBMB Enzyme Nomenclature | 1.3.1.94 |
| IntEnz | 1.3.1.94 |
| MEDLINE | Find literature relating to 1.3.1.94 |
| MetaCyc | 1.3.1.94 |
| UniProtKB/Swiss-Prot |
| P40526, DFG10_YEAST; | Q9CAH5, POED1_ARATH; | A2XWN6, POED1_ORYSI; |
| Q7XUH5, POED1_ORYSJ; | Q9SI62, POED2_ARATH; | B8B6G5, POED2_ORYSI; |
| Q7F0Q2, POED2_ORYSJ; | D2HBV9, PORED_AILME; | A8X8R3, PORED_CAEBR; |
| Q17428, PORED_CAEEL; | Q5RIU9, PORED_DANRE; | Q9VLP9, PORED_DROME; |
| Q9H8P0, PORED_HUMAN; | C7T2J9, PORED_MESAU; | Q9WUP4, PORED_MOUSE; |
| Q5RJM1, PORED_RAT; | Q8AVI9, PORED_XENLA; | Q0P4J9, PORED_XENTR; |
|
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