ENZYME entry: EC 1.3.3.10

Accepted Name
Tryptophan alpha,beta-oxidase.
Alternative Name(s)
L-tryptophan 2',3'-oxidase.
L-tryptophan alpha,beta-dehydrogenase.
Reaction catalysed
L-tryptophan + O(2) <=> alpha,beta-didehydrotryptophan + H(2)O(2)
Cofactor(s)
Heme.
Comment(s)
  • The enzyme from Chromobacterium violaceum is specific for tryptophan derivatives possessing its carboxyl group free or as an amide or ester, and an unsubstituted indole ring.
  • Also catalyzes the alpha,beta dehydrogenation of L-tryptophan side chains in peptides.
  • The product of the reaction can hydrolyze spontaneously to form indolepyruvate.
  • Formerly EC 1.4.3.17.
Cross-references
BRENDA1.3.3.10
EC2PDB1.3.3.10
ExplorEnz1.3.3.10
PRIAM enzyme-specific profiles1.3.3.10
KEGG Ligand Database for Enzyme Nomenclature1.3.3.10
IUBMB Enzyme Nomenclature1.3.3.10
IntEnz1.3.3.10
MEDLINEFind literature relating to 1.3.3.10
MetaCyc1.3.3.10

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