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ENZYME entry: EC 1.3.7.5

Accepted Name
Phycocyanobilin:ferredoxin oxidoreductase.
Reaction catalysed
(3Z)-phycocyanobilin + 4 oxidized ferredoxin <=> biliverdin IX-alpha + 4 reduced ferredoxin
Comment(s)
  • Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings).
  • Reaction proceeds via an isolatable 2-electron intermediate, 18(1),18(2)-dihydrobiliverdin.
  • Flavodoxins can be used instead of ferredoxin.
  • The direct conversion of biliverdin IX-alpha (BV) to (3Z)- phycocyanobilin (PCB) in the cyanobacteria Synechocystis sp. PCC 6803, Anabaena sp. PCC7120 and Nostoc punctiforme is in contrast to the proposed pathways of PCB biosynthesis in the red alga Cyanidium caldarium, which involves (3Z)-phycoerythrobilin (PEB) as an intermediate and in the green alga Mesotaenium caldariorum, in which PCB is an isolable intermediate.
Cross-references
BRENDA1.3.7.5
EC2PDB1.3.7.5
ExplorEnz1.3.7.5
PRIAM enzyme-specific profiles1.3.7.5
KEGG Ligand Database for Enzyme Nomenclature1.3.7.5
IUBMB Enzyme Nomenclature1.3.7.5
IntEnz1.3.7.5
MEDLINEFind literature relating to 1.3.7.5
MetaCyc1.3.7.5
UniProtKB/Swiss-Prot
Q3M745, PCYA_ANAVT;  B1X018, PCYA_CYAA5;  B7KJQ2, PCYA_CYAP7;  
B7JWS2, PCYA_CYAP8;  Q7NHE8, PCYA_GLOVI;  B0JPG5, PCYA_MICAN;  
Q93TM9, PCYA_NOSP7;  Q93TN0, PCYA_NOSS1;  A3PCF5, PCYA_PROM0;  
A8G4C5, PCYA_PROM2;  A2CA92, PCYA_PROM3;  A2BW83, PCYA_PROM5;  
Q31BD0, PCYA_PROM9;  Q7VCC2, PCYA_PROMA;  Q7V7Y8, PCYA_PROMM;  
Q93TL5, PCYA_PROMP;  A2BQN3, PCYA_PROMS;  Q8KPS9, PCYA_SYNE7;  
Q5N5A3, PCYA_SYNP6;  Q7U7A1, PCYA_SYNPX;  Q3AXI3, PCYA_SYNS9;  
Q3AKB1, PCYA_SYNSC;  Q55891, PCYA_SYNY3;  P59288, PCYA_THEEB;  
Q10X61, PCYA_TRIEI;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.7.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-