ENZYME entry: EC 1.3.7.7

Accepted Name
Ferredoxin:protochlorophyllide reductase (ATP-dependent).
Alternative Name(s)
Light-independent protochlorophyllide reductase.
Reaction catalysed
Protochlorophyllide a + reduced ferredoxin + 2 ATP + 2 H(2)O <=> chlorophyllide a + oxidized ferredoxin + 2 ADP + 2 phosphate
Cofactor(s)
Iron-sulfur.
Comment(s)
  • Occurs in photosynthetic bacteria, cyanobacteria, green algae and gymnosperms.
  • The enzyme catalyzes trans-reduction of the D-ring of protochlorophyllide; the product has the (7S,8S)-configuration.
  • Unlike EC 1.3.1.33 light is not required.
  • The enzyme contains a [4Fe-4S] cluster, and structurally resembles the Fe protein/MoFe protein complex of EC 1.18.6.1, which catalyzes an ATP-driven reduction.
Cross-references
BRENDA1.3.7.7
EC2PDB1.3.7.7
ExplorEnz1.3.7.7
PRIAM enzyme-specific profiles1.3.7.7
KEGG Ligand Database for Enzyme Nomenclature1.3.7.7
IUBMB Enzyme Nomenclature1.3.7.7
IntEnz1.3.7.7
MEDLINEFind literature relating to 1.3.7.7
MetaCyc1.3.7.7
UniProtKB/Swiss-Prot
Q9WXB5, BCHB_ACIRU;  A5EQ82, BCHB_BRASB;  A4YNP2, BCHB_BRASO;  
Q9F6X5, BCHB_CHLAA;  B8G945, BCHB_CHLAD;  Q3APL0, BCHB_CHLCH;  
B3EGV4, BCHB_CHLL2;  Q3B6C7, BCHB_CHLL7;  B3QQZ3, BCHB_CHLP8;  
B3EP24, BCHB_CHLPB;  A1BIZ8, BCHB_CHLPD;  A4SCU5, BCHB_CHLPM;  
B9LKM4, BCHB_CHLSY;  B3QZE2, BCHB_CHLT3;  Q9F715, BCHB_CHLTE;  
A8LQ28, BCHB_DINSH;  A1WXI8, BCHB_HALHL;  B0TBM8, BCHB_HELMI;  
Q9ZGE8, BCHB_HELMO;  Q28W35, BCHB_JANSC;  B1LSG1, BCHB_METRJ;  
B0UDK6, BCHB_METS4;  B8EPX7, BCHB_METSB;  B4SC78, BCHB_PELPB;  
B4S592, BCHB_PROA2;  P26163, BCHB_RHOCB;  Q2ISY7, BCHB_RHOP2;  
Q07RY4, BCHB_RHOP5;  Q6N9K2, BCHB_RHOPA;  Q219R0, BCHB_RHOPB;  
Q132N3, BCHB_RHOPS;  B3Q7C5, BCHB_RHOPT;  Q2RWR9, BCHB_RHORT;  
A3PL17, BCHB_RHOS1;  Q9Z5D9, BCHB_RHOS4;  A4WR96, BCHB_RHOS5;  
B9KK25, BCHB_RHOSK;  A7NJG0, BCHB_ROSCS;  Q16DS0, BCHB_ROSDO;  
A5UUJ5, BCHB_ROSS1;  Q9JPA3, BCHB_RUBGI;  Q9WXB7, BCHL_ACIRU;  
A5EQ80, BCHL_BRASB;  A4YNP4, BCHL_BRASO;  Q9F6X3, BCHL_CHLAA;  
B8G943, BCHL_CHLAD;  Q3APL1, BCHL_CHLCH;  B3EGV3, BCHL_CHLL2;  
Q3B6C6, BCHL_CHLL7;  B3QQZ4, BCHL_CHLP8;  B3ENS3, BCHL_CHLPB;  
A1BIZ7, BCHL_CHLPD;  A4SCU6, BCHL_CHLPM;  B9LKM2, BCHL_CHLSY;  
B3QZE1, BCHL_CHLT3;  Q9F714, BCHL_CHLTE;  A8LQ30, BCHL_DINSH;  
A1WXI6, BCHL_HALHL;  B0TBM6, BCHL_HELMI;  Q9ZGF0, BCHL_HELMO;  
Q28W37, BCHL_JANSC;  B7KVV7, BCHL_METC4;  A9W9E2, BCHL_METEP;  
B1ZBP2, BCHL_METPB;  B1LSF9, BCHL_METRJ;  B0UDK8, BCHL_METS4;  
B8EPX5, BCHL_METSB;  B4SC79, BCHL_PELPB;  B4S591, BCHL_PROA2;  
P0CY53, BCHL_RHOCA;  D5ANS3, BCHL_RHOCB;  B6ITW5, BCHL_RHOCS;  
Q2ISY9, BCHL_RHOP2;  Q07RY2, BCHL_RHOP5;  Q6N9K0, BCHL_RHOPA;  
Q219Q8, BCHL_RHOPB;  Q132N5, BCHL_RHOPS;  Q2RWS1, BCHL_RHORT;  
Q9L8J5, BCHL_RHORU;  A3PL19, BCHL_RHOS1;  Q9RFD6, BCHL_RHOS4;  
A4WR94, BCHL_RHOS5;  B9KK27, BCHL_RHOSK;  A7NJG1, BCHL_ROSCS;  
Q16DS2, BCHL_ROSDO;  A5UUJ4, BCHL_ROSS1;  Q9JPA5, BCHL_RUBGI;  
Q9WXB4, BCHN_ACIRU;  A5EQ83, BCHN_BRASB;  A4YNP1, BCHN_BRASO;  
Q9F6X6, BCHN_CHLAA;  Q3APK9, BCHN_CHLCH;  Q3B6C8, BCHN_CHLL7;  
A1BIZ9, BCHN_CHLPD;  B3QZE3, BCHN_CHLT3;  Q9F716, BCHN_CHLTE;  
A8LQ27, BCHN_DINSH;  A1WXI9, BCHN_HALHL;  B0TBM7, BCHN_HELMI;  
Q9ZGE9, BCHN_HELMO;  Q28W34, BCHN_JANSC;  P26164, BCHN_RHOCB;  
Q2ISY6, BCHN_RHOP2;  Q07RY5, BCHN_RHOP5;  Q6N9K3, BCHN_RHOPA;  
Q219R1, BCHN_RHOPB;  Q132N2, BCHN_RHOPS;  B3Q7C4, BCHN_RHOPT;  
Q2RWR8, BCHN_RHORT;  A3PL16, BCHN_RHOS1;  Q9RFD4, BCHN_RHOS4;  
A4WR97, BCHN_RHOS5;  B9KK24, BCHN_RHOSK;  A7NJF9, BCHN_ROSCS;  
Q16DR9, BCHN_ROSDO;  A5UUJ6, BCHN_ROSS1;  Q9JPA2, BCHN_RUBGI;  
B0C929, CHLB_ACAM1;  Q1KVW2, CHLB_ACUOB;  Q85FN8, CHLB_ADICA;  
Q3M7G3, CHLB_ANAVT;  A2T312, CHLB_ANGEV;  Q85AC2, CHLB_ANTFO;  
P37843, CHLB_ARAHE;  Q6VQA8, CHLB_AUXPR;  P37844, CHLB_BAZTR;  
Q8MA01, CHLB_CHAGL;  Q1ACL5, CHLB_CHAVU;  P37823, CHLB_CHLAP;  
Q19V92, CHLB_CHLAT;  P17652, CHLB_CHLMO;  P37824, CHLB_CHLPT;  
P36437, CHLB_CHLRE;  P56302, CHLB_CHLVU;  Q32067, CHLB_CIBSC;  
B1X0L5, CHLB_CYAA5;  Q33076, CHLB_CYACO;  B8HSK3, CHLB_CYAP4;  
B7KC04, CHLB_CYAP7;  B7JV38, CHLB_CYAP8;  P48099, CHLB_CYAPA;  
A6H5E7, CHLB_CYCTA;  P37848, CHLB_DIPCM;  P37846, CHLB_EPHAL;  
P37845, CHLB_EQUAR;  Q32214, CHLB_EQUSC;  P36208, CHLB_GINBI;  
Q7NP43, CHLB_GLOVI;  Q5SCX2, CHLB_HUPLU;  Q32450, CHLB_ISOEC;  
P95463, CHLB_LEPBY;  A6YGA3, CHLB_LEPTE;  P37847, CHLB_LYCAN;  
P26238, CHLB_MARPO;  Q9MUR9, CHLB_MESVI;  P37849, CHLB_METGY;  
B0JGE2, CHLB_MICAN;  P37850, CHLB_NEPEX;  Q9T467, CHLB_NEPOL;  
B2J0C5, CHLB_NOSP7;  Q8YRK5, CHLB_NOSS1;  Q20EY2, CHLB_OLTVI;  
P37851, CHLB_OSMCL;  Q6YXN5, CHLB_PHYPA;  P37853, CHLB_PICMA;  
Q85X76, CHLB_PINKO;  Q95666, CHLB_PINST;  Q00864, CHLB_PINTH;  
P37854, CHLB_PLESC;  P37852, CHLB_POLCU;  P51278, CHLB_PORPU;  
A3PBR8, CHLB_PROM0;  A2C101, CHLB_PROM1;  A8G3Q9, CHLB_PROM2;  
A2C7T5, CHLB_PROM3;  A9BEG7, CHLB_PROM4;  A2BVK6, CHLB_PROM5;  
Q31BZ0, CHLB_PROM9;  Q7VD38, CHLB_PROMA;  Q7V6E8, CHLB_PROMM;  
Q7V2D6, CHLB_PROMP;  A2BQ25, CHLB_PROMS;  Q46GN4, CHLB_PROMT;  
Q1XDK8, CHLB_PYRYE;  P37855, CHLB_SALAU;  P37856, CHLB_SELMO;  
Q33093, CHLB_STAER;  Q32RS2, CHLB_STAPU;  Q06SE5, CHLB_STIHE;  
Q8GJN0, CHLB_SYNE7;  Q2JVX9, CHLB_SYNJA;  Q2JJM9, CHLB_SYNJB;  
B1XP49, CHLB_SYNP2;  Q5MZS4, CHLB_SYNP6;  A5GJI2, CHLB_SYNPW;  
Q7U5I3, CHLB_SYNPX;  A5GUA9, CHLB_SYNR3;  Q0I8P5, CHLB_SYNS3;  
Q3AWT5, CHLB_SYNS9;  Q3ALL7, CHLB_SYNSC;  Q55607, CHLB_SYNY3;  
Q8DGC6, CHLB_THEEB;  Q10Y17, CHLB_TRIEI;  P37857, CHLB_ZAMFI;  
Q32RP9, CHLB_ZYGCR;  B0C7T2, CHLL_ACAM1;  Q1KVR9, CHLL_ACUOB;  
Q85FG5, CHLL_ADICA;  Q3MAN6, CHLL_ANAVT;  A2T392, CHLL_ANGEV;  
Q85A82, CHLL_ANTFO;  Q6VQA9, CHLL_AUXPR;  Q8LU58, CHLL_CHAGL;  
Q1ACE0, CHLL_CHAVU;  Q19V52, CHLL_CHLAT;  Q00469, CHLL_CHLRE;  
P56291, CHLL_CHLVU;  B8HUQ3, CHLL_CYAP4;  B7JYK3, CHLL_CYAP8;  
P48110, CHLL_CYAPA;  A6H5Q2, CHLL_CYCTA;  Q7NI14, CHLL_GLOVI;  
Q5SCY9, CHLL_HUPLU;  Q695L6, CHLL_LARDC;  Q00237, CHLL_LEPBY;  
A6YGA4, CHLL_LEPTE;  P06267, CHLL_MARPO;  Q9MUM2, CHLL_MESVI;  
B0JVB1, CHLL_MICAN;  Q9T399, CHLL_NEPOL;  B2IUL7, CHLL_NOSP7;  
Q8YM62, CHLL_NOSS1;  Q20EX9, CHLL_OLTVI;  Q6YXQ7, CHLL_PHYPA;  
O47041, CHLL_PICAB;  P26181, CHLL_PINCO;  Q85WT6, CHLL_PINKO;  
P41645, CHLL_PINTH;  P36439, CHLL_POLAC;  P51187, CHLL_PORPU;  
A3PBR7, CHLL_PROM0;  A2C0Z9, CHLL_PROM1;  A8G3Q8, CHLL_PROM2;  
A2C7T4, CHLL_PROM3;  A9BEG6, CHLL_PROM4;  A2BVK5, CHLL_PROM5;  
Q31BZ1, CHLL_PROM9;  Q7VD39, CHLL_PROMA;  Q7V6E7, CHLL_PROMM;  
Q7V2D7, CHLL_PROMP;  A2BQ24, CHLL_PROMS;  Q46GN6, CHLL_PROMT;  
Q1XDV0, CHLL_PYRYE;  Q32RZ7, CHLL_STAPU;  Q06SC7, CHLL_STIHE;  
P54207, CHLL_SYNE7;  Q2JS74, CHLL_SYNJA;  Q2JMP3, CHLL_SYNJB;  
Q53450, CHLL_SYNP2;  Q5N5U1, CHLL_SYNP6;  A5GJI1, CHLL_SYNPW;  
Q7U5I2, CHLL_SYNPX;  A5GUB0, CHLL_SYNR3;  Q0I8P4, CHLL_SYNS3;  
Q3AWT4, CHLL_SYNS9;  Q3ALL9, CHLL_SYNSC;  P28373, CHLL_SYNY3;  
Q8DGH0, CHLL_THEEB;  Q115L1, CHLL_TRIEI;  Q32RK7, CHLL_ZYGCR;  
B0C7T1, CHLN_ACAM1;  Q1KVX6, CHLN_ACUOB;  Q85FG6, CHLN_ADICA;  
Q3MAN8, CHLN_ANAVT;  A2T391, CHLN_ANGEV;  Q85A72, CHLN_ANTFO;  
Q7YKW4, CHLN_AUXPR;  Q8LW53, CHLN_CHAGL;  Q1ACE1, CHLN_CHAVU;  
Q19V53, CHLN_CHLAT;  P29683, CHLN_CHLRE;  P56303, CHLN_CHLVU;  
P48100, CHLN_CYAPA;  A6H5Q1, CHLN_CYCTA;  Q7NI15, CHLN_GLOVI;  
Q5SCY8, CHLN_HUPLU;  Q04607, CHLN_LEPBY;  A6YGA5, CHLN_LEPTE;  
P26156, CHLN_MARPO;  Q9MUM1, CHLN_MESVI;  Q9T4F6, CHLN_NEPOL;  
Q8YM64, CHLN_NOSS1;  Q20EX8, CHLN_OLTVI;  Q6YXP4, CHLN_PHYPA;  
P26180, CHLN_PINCO;  Q85WU5, CHLN_PINKO;  P41646, CHLN_PINTH;  
P51188, CHLN_PORPU;  A3PBR9, CHLN_PROM0;  A2C100, CHLN_PROM1;  
A8G3R0, CHLN_PROM2;  A2C7T6, CHLN_PROM3;  A9BEG8, CHLN_PROM4;  
A2BVK7, CHLN_PROM5;  Q31BY9, CHLN_PROM9;  Q7VD37, CHLN_PROMA;  
Q7V6E9, CHLN_PROMM;  Q7V2D5, CHLN_PROMP;  A2BQ26, CHLN_PROMS;  
Q46GN5, CHLN_PROMT;  Q1XDU9, CHLN_PYRYE;  Q32RZ8, CHLN_STAPU;  
Q06SE3, CHLN_STIHE;  P54208, CHLN_SYNE7;  Q2JS72, CHLN_SYNJA;  
Q2JMP5, CHLN_SYNJB;  Q5N5U2, CHLN_SYNP6;  A5GJI3, CHLN_SYNPW;  
Q7U5I4, CHLN_SYNPX;  A5GUA8, CHLN_SYNR3;  Q0I8P6, CHLN_SYNS3;  
Q3AWT6, CHLN_SYNS9;  Q3ALL6, CHLN_SYNSC;  P28372, CHLN_SYNY3;  
Q8DGH2, CHLN_THEEB;  Q115L3, CHLN_TRIEI;  Q32RK6, CHLN_ZYGCR;  

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