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ENZYME entry: EC 1.3.8.2

Accepted Name
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming).
Alternative Name(s)
4,4'-diapophytoene desaturase.
Dehydrosqualene desaturase.
Reaction catalysed
15-cis-4,4'-diapophytoene + 4 FAD <=> all-trans-4,4'-diapolycopene + 4 FADH(2)
Comment(s)
  • The enzyme catalyzes four successive dehydrogenations, resulting in production of 4,4'-diapolycopene.
  • While the enzyme from Staphylococcus aureus was only shown to produce 4,4'-diaponeurosporene in vivo, it is able to catalyze the last reaction in vitro.
Cross-references
BRENDA1.3.8.2
EC2PDB1.3.8.2
ExplorEnz1.3.8.2
PRIAM enzyme-specific profiles1.3.8.2
KEGG Ligand Database for Enzyme Nomenclature1.3.8.2
IUBMB Enzyme Nomenclature1.3.8.2
IntEnz1.3.8.2
MEDLINEFind literature relating to 1.3.8.2
MetaCyc1.3.8.2
UniProtKB/Swiss-Prot
Q2FDU6, CRTN_STAA3;  Q2FV60, CRTN_STAA8;  Q2YWE8, CRTN_STAAB;  
Q5HCY9, CRTN_STAAC;  O07855, CRTN_STAAE;  Q99R76, CRTN_STAAM;  
Q7A3E2, CRTN_STAAN;  Q6GDN7, CRTN_STAAR;  Q6G6B3, CRTN_STAAS;  
Q8NUQ6, CRTN_STAAW;  Q4L975, CRTN_STAHJ;  

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-