Due to maintenance work, this service will not be available from Monday June 27th 5.00 pm until Monday June 27th 9.00 pm CEST.

ENZYME entry: EC 1.3.8.3

Accepted Name
(R)-benzylsuccinyl-CoA dehydrogenase.
Reaction catalysed
(R)-2-benzylsuccinyl-CoA + electron-transfer flavoprotein <=> (E)-2-benzylidenesuccinyl-CoA + reduced electron-transfer flavoprotein
Cofactor(s)
FAD.
Comment(s)
  • Unlike other acyl-CoA dehydrogenases, this enzyme exhibits high substrate- and enantiomer specificity it is highly specific for (R)- benzylsuccinyl-CoA and is inhibited by (S)-benzylsuccinyl-CoA.
  • Forms the third step in the anaerobic toluene metabolic pathway in Thauera aromatica.
  • Ferricenium ion is an effective artificial electron acceptor.
  • Formerly EC 1.3.99.21.
Cross-references
PROSITEPDOC00070
BRENDA1.3.8.3
EC2PDB1.3.8.3
ExplorEnz1.3.8.3
PRIAM enzyme-specific profiles1.3.8.3
KEGG Ligand Database for Enzyme Nomenclature1.3.8.3
IUBMB Enzyme Nomenclature1.3.8.3
IntEnz1.3.8.3
MEDLINEFind literature relating to 1.3.8.3
MetaCyc1.3.8.3
UniProtKB/Swiss-Prot
Q9KJE8, BBSG_THAAR

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.8.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-