ID 1.3.98.4 DE 5a,11a-dehydrotetracycline reductase. AN 12-dehydrotetracycline dehydrogenase. AN 12-dehydrotetracycline reductase. AN dehydrooxytetracycline dehydrogenase. CA H(+) + oxidized coenzyme F420-(gamma-L-Glu)(n) + tetracycline = 5a,11a- CA dehydrotetracycline + reduced coenzyme F420-(gamma-L-Glu)(n). CC -!- The enzyme, characterized from the bacteria Streptomyces aureofaciens CC and Streptomyces rimosus, catalyzes the last step in the biosynthesis CC of the tetracycline antibiotics tetracycline and oxytetracycline. DR L8EYU3, OXYR_STRR1 ; //