ENZYME entry: EC 1.3.99.24

Accepted Name
2-amino-4-deoxychorismate dehydrogenase.
Alternative Name(s)
2-amino-2-deoxyisochorismate dehydrogenase.
ADIC dehydrogenase.
Reaction catalysed
(2S)-2-amino-4-deoxychorismate + FMN <=> 3-(1-carboxyvinyloxy)anthranilate + FMNH(2)
Comment(s)
The sequential action of EC 2.6.1.86 and this enzyme leads to the formation of the benzoxazolinate moiety of the enediyne antitumor antibiotic C-1027.
Cross-references
BRENDA1.3.99.24
EC2PDB1.3.99.24
ExplorEnz1.3.99.24
PRIAM enzyme-specific profiles1.3.99.24
KEGG Ligand Database for Enzyme Nomenclature1.3.99.24
IUBMB Enzyme Nomenclature1.3.99.24
IntEnz1.3.99.24
MEDLINEFind literature relating to 1.3.99.24
MetaCyc1.3.99.24
UniProtKB/Swiss-Prot
Q8GMH2, SGCG_STRGL

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