ENZYME entry: EC 1.3.99.5

Accepted Name
3-oxo-5-alpha-steroid 4-dehydrogenase (acceptor).
Alternative Name(s)
Steroid 5-alpha-reductase.
Reaction catalysed
A 3-oxo-5-alpha-steroid + acceptor <=> a 3-oxo-Delta(4)-steroid + reduced acceptor
Cofactor(s)
Flavoprotein.
Comment(s)
  • This bacterial enzyme, characterized from Comamonas testosteroni, is involved in androsterone degradation.
  • Cf. EC 1.3.1.22.
Cross-references
BRENDA1.3.99.5
EC2PDB1.3.99.5
ExplorEnz1.3.99.5
PRIAM enzyme-specific profiles1.3.99.5
KEGG Ligand Database for Enzyme Nomenclature1.3.99.5
IUBMB Enzyme Nomenclature1.3.99.5
IntEnz1.3.99.5
MEDLINEFind literature relating to 1.3.99.5
MetaCyc1.3.99.5
UniProtKB/Swiss-Prot
Q59327, OASD_COMTE

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