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ENZYME

ENZYME entry: EC 1.4.1.28

Accepted Name
secondary-alkyl amine dehydrogenase [NAD(P)(+)]
Alternative Name(s)
amine dehydrogenase
Reaction catalysed
  • a secondary alkyl amine + H2O + NAD(+) <=> a ketone + H(+) + NADH + NH4(+)
  • a secondary alkyl amine + H2O + NADP(+) <=> a ketone + H(+) + NADPH + NH4(+)
Comment(s)
  • The enzyme has been shown to react preferentially with short-chain ketones such as cyclohexanone, primary amine groups attached to secondary alkyl groups, or D- and L-amino acids.
  • It also reduces aldehydes to primary amines.
  • Cosubstrate preference depends on the substrate.
Cross-references
BRENDA1.4.1.28
EC2PDB1.4.1.28
ExplorEnz1.4.1.28
PRIAM enzyme-specific profiles1.4.1.28
KEGG Ligand Database for Enzyme Nomenclature1.4.1.28
IUBMB Enzyme Nomenclature1.4.1.28
IntEnz1.4.1.28
MEDLINEFind literature relating to 1.4.1.28
MetaCyc1.4.1.28
Rhea expert-curated reactions1.4.1.28
UniProtKB/Swiss-Prot
A0A0L8M630, AMDH_STRVG

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