ENZYME entry: EC 1.4.3.23
| Accepted Name |
|---|
| 7-chloro-L-tryptophan oxidase.
|
| Reaction catalysed |
|---|
| 7-chloro-L-tryptophan + O(2) <=> 2-imino-3-(7-chloroindol-3-yl)propanoate + H(2)O(2) |
| Comment(s) |
|---|
- This enzyme catalyzes a step in the biosynthesis of rebeccamycin,
an indolocarbazole alkaloid produced by the actinobacterium
Lechevalieria aerocolonigenes.
- During catalysis, the bound FAD is reoxidized at the expense of
molecular oxygen, producing one molecule of hydrogen peroxide.
- The enzyme shows significant preference for 7-chloro-L-tryptophan
over L-tryptophan.
|
| Cross-references |
|---|
| BRENDA | 1.4.3.23 |
| EC2PDB | 1.4.3.23 |
| ExplorEnz | 1.4.3.23 |
| PRIAM enzyme-specific profiles | 1.4.3.23 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.4.3.23 |
| IUBMB Enzyme Nomenclature | 1.4.3.23 |
| IntEnz | 1.4.3.23 |
| MEDLINE | Find literature relating to 1.4.3.23 |
| MetaCyc | 1.4.3.23 |
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