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ENZYME

ENZYME entry: EC 1.4.3.27

Accepted Name
homospermidine oxidase
Reaction catalysed
H2O + 2 O2 + sym-homospermidine <=> 1-formylpyrrolizidine + 2 H2O2 + 2 NH4(+)
Comment(s)
  • The copper-containing enzyme has been isolated from the plant Heliotropium indicum.
  • It is involved in the biosynthesis of the pyrrolizidine alkaloid (-)- trachelanthamidine which acts as a secondary metabolite for the defense against herbivores.
  • The oxidation of sym-homospermidine proceeds in three steps and results in a cyclization.
Cross-references
BRENDA1.4.3.27
EC2PDB1.4.3.27
ExplorEnz1.4.3.27
PRIAM enzyme-specific profiles1.4.3.27
KEGG Ligand Database for Enzyme Nomenclature1.4.3.27
IUBMB Enzyme Nomenclature1.4.3.27
IntEnz1.4.3.27
MEDLINEFind literature relating to 1.4.3.27
MetaCyc1.4.3.27
Rhea expert-curated reactions1.4.3.27

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