ID 1.4.3.27 DE homospermidine oxidase. CA H2O + 2 O2 + sym-homospermidine = 1-formylpyrrolizidine + 2 H2O2 + CA 2 NH4(+). CC -!- The copper-containing enzyme has been isolated from the plant CC Heliotropium indicum. CC -!- It is involved in the biosynthesis of the pyrrolizidine alkaloid (-)- CC trachelanthamidine which acts as a secondary metabolite for the CC defense against herbivores. CC -!- The oxidation of sym-homospermidine proceeds in three steps and CC results in a cyclization. //