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ENZYME entry: EC

Accepted Name
1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NAD(P)H).
Alternative Name(s)
Pyrroline-2-carboxylate reductase.
Reaction catalysed
  • L-pipecolate + NAD(P)(+) <=> 1-piperideine-2-carboxylate + NAD(P)H
  • L-proline + NAD(P)(+) <=> 1-pyrroline-2-carboxylate + NAD(P)H
  • The enzymes, characterized from the bacterium Azospirillum brasilense, is involved in trans-3-hydroxy-L-proline metabolism.
  • In contrast to EC, which is specific for NADPH, this enzyme shows similar activity with NADPH and NADH.
PRIAM enzyme-specific profiles1.5.1.1
KEGG Ligand Database for Enzyme Nomenclature1.5.1.1
IUBMB Enzyme Nomenclature1.5.1.1
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