ID   1.5.1.3
DE   Dihydrofolate reductase.
AN   Tetrahydrofolate dehydrogenase.
CA   5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + NADPH.
CC   -!- The enzyme from animals and some micro-organisms also slowly reduces
CC       folate to 5,6,7,8-tetrahydrofolate.
CC   -!- Formerly EC 1.5.1.4.
PR   PROSITE; PDOC00072;
DR   Q05762, DRTS1_ARATH;  Q05763, DRTS2_ARATH;  Q23695, DRTS_CRIFA ;
DR   P45350, DRTS_DAUCA ;  P16126, DRTS_LEIAM ;  P07382, DRTS_LEIMA ;
DR   O81395, DRTS_MAIZE ;  Q5UQG3, DRTS_MIMIV ;  Q2QRX6, DRTS_ORYSJ ;
DR   Q27828, DRTS_PARTE ;  Q27713, DRTS_PLABA ;  P20712, DRTS_PLACH ;
DR   P13922, DRTS_PLAFK ;  O02604, DRTS_PLAVI ;  P46103, DRTS_PLAVN ;
DR   P51820, DRTS_SOYBN ;  Q07422, DRTS_TOXGO ;  Q27783, DRTS_TRYBB ;
DR   Q27793, DRTS_TRYCR ;  Q04515, DYR10_ECOLX;  Q59408, DYR13_ECOLX;
DR   P78218, DYR15_ECOLX;  P00382, DYR1_ECOLX ;  Q5V3R2, DYR1_HALMA ;
DR   P00383, DYR21_ECOLX;  P00384, DYR22_ECOLX;  P05794, DYR23_ECOLX;
DR   Q5V600, DYR2_HALMA ;  P12833, DYR3_SALTM ;  P11731, DYR5_ECOLX ;
DR   P95524, DYR6_PROMI ;  P27422, DYR7_ECOLX ;  P0ABQ7, DYR8_ECOLX ;
DR   P0ABQ8, DYR8_SHISO ;  Q59397, DYR9_ECOLX ;  P13955, DYRA_STAAU ;
DR   Q86XF0, DYRL1_HUMAN;  P28019, DYR_AEDAL  ;  P11045, DYR_BACSU  ;
DR   P00376, DYR_BOVIN  ;  P04382, DYR_BPT4   ;  P57243, DYR_BUCAI  ;
DR   Q8K9Z8, DYR_BUCAP  ;  Q89AV2, DYR_BUCBP  ;  Q93341, DYR_CAEEL  ;
DR   P22906, DYR_CANAX  ;  P00378, DYR_CHICK  ;  P31073, DYR_CITFR  ;
DR   Q07801, DYR_CRYNJ  ;  P17719, DYR_DROME  ;  P0ABQ5, DYR_ECOL6  ;
DR   P0ABQ4, DYR_ECOLI  ;  O62583, DYR_ENCCU  ;  P31074, DYR_ENTAE  ;
DR   P00380, DYR_ENTFC  ;  P43791, DYR_HAEIN  ;  P15093, DYR_HALVD  ;
DR   Q9U8B8, DYR_HELVI  ;  P00374, DYR_HUMAN  ;  P00381, DYR_LACCA  ;
DR   Q59487, DYR_LACLA  ;  P04753, DYR_MESAU  ;  P00375, DYR_MOUSE  ;
DR   P0A547, DYR_MYCBO  ;  P47470, DYR_MYCGE  ;  Q9CBW1, DYR_MYCLE  ;
DR   P78028, DYR_MYCPN  ;  Q98Q32, DYR_MYCPU  ;  P0A546, DYR_MYCTU  ;
DR   P04174, DYR_NEIGO  ;  Q9JSQ9, DYR_NEIMA  ;  Q9K168, DYR_NEIMB  ;
DR   P00377, DYR_PIG    ;  P16184, DYR_PNECA  ;  Q920D2, DYR_RAT    ;
DR   P36591, DYR_SCHPO  ;  P0ABQ6, DYR_SHIFL  ;  P09503, DYR_SHV21  ;
DR   P27421, DYR_SHV24  ;  P22573, DYR_SHV2C  ;  Q5HFZ7, DYR_STAAC  ;
DR   P0A016, DYR_STAAM  ;  P99079, DYR_STAAN  ;  Q6GGY1, DYR_STAAR  ;
DR   Q6G9D5, DYR_STAAS  ;  P0A017, DYR_STAAU  ;  Q8NWQ9, DYR_STAAW  ;
DR   P0C0P0, DYR_STAEP  ;  Q5HPB1, DYR_STAEQ  ;  P0C0P1, DYR_STAES  ;
DR   Q54277, DYR_STAHA  ;  Q54801, DYR_STRPN  ;  Q60034, DYR_THEMA  ;
DR   Q9PR30, DYR_UREPA  ;  P07807, DYR_YEAST  ;  A8AGY5, FOLM_CITK8 ;
DR   A7ZM66, FOLM_ECO24 ;  P0AFS4, FOLM_ECO57 ;  A8A0E8, FOLM_ECOHS ;
DR   A1ABF1, FOLM_ECOK1 ;  Q0THM2, FOLM_ECOL5 ;  Q8FHB1, FOLM_ECOL6 ;
DR   B1IQY4, FOLM_ECOLC ;  P0AFS3, FOLM_ECOLI ;  B1LET0, FOLM_ECOSM ;
DR   Q1RBJ2, FOLM_ECOUT ;  A4W9Z4, FOLM_ENT38 ;  A6T8N3, FOLM_KLEP7 ;
DR   Q320W2, FOLM_SHIBS ;  Q32G72, FOLM_SHIDS ;  Q0T4H1, FOLM_SHIF8 ;
DR   Q83RC9, FOLM_SHIFL ;  Q3Z1V9, FOLM_SHISS ;
//