ID   1.5.1.43
DE   carboxynorspermidine synthase.
AN   carboxynorspermidine dehydrogenase.
AN   carboxyspermidine dehydrogenase.
CA   (1) carboxynorspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde +
CA   propane-1,3-diamine + NADPH + H(+).
CA   (2) carboxyspermidine + NADP(+) + H2O = L-aspartate 4-semialdehyde +
CA   putrescine + NADPH + H(+).
CC   -!- The reaction takes place in the opposite direction.
CC   -!- Part of a bacterial polyamine biosynthesis pathway.
CC   -!- L-aspartate 4-semialdehyde and propane-1,3-diamine/putrescine form a
CC       Schiff base that is reduced to form
CC       carboxynorspermidine/carboxyspermidine, respectively.
CC   -!- The enzyme from the bacterium Vibrio cholerae is essential for
CC       biofilm formation.
CC   -!- The enzyme from Campylobacter jejuni only produces carboxyspermidine
CC       in vivo even though it also can produce carboxynorspermidine in
CC       vitro.
DR   P0DPE4, CANSD_VIBAX;  Q9KRL3, CANSD_VIBCH;
//