ID   1.5.1.47
DE   dihydromethanopterin reductase [NAD(P)(+)].
AN   5,6,7,8-tetrahydromethanopterin 5,6-oxidoreductase.
AN   dihydromethanopterin reductase.
AN   H2MPT reductase.
CA   (1) 5,6,7,8-tetrahydromethanopterin + NADP(+) = 7,8-dihydromethanopterin
CA   + H(+) + NADPH.
CA   (2) 5,6,7,8-tetrahydromethanopterin + NAD(+) = 7,8-dihydromethanopterin +
CA   H(+) + NADH.
CC   -!- The enzyme, characterized from the bacterium Methylobacterium
CC       extorquens, is involved in biosynthesis of dephospho-
CC       tetrahydromethanopterin.
CC   -!- The specific activity with NADH is 15% of that with NADPH at the same
CC       concentration.
CC   -!- It does not reduce 7,8-dihydrofolate (cf. EC 1.5.1.3).
DR   C5B2R8, DMRA_METEA ;
//