ID   1.5.1.49
DE   1-pyrroline-2-carboxylate reductase [NAD(P)H].
CA   (1) L-proline + NADP(+) = 1-pyrroline-2-carboxylate + H(+) + NADPH.
CA   (2) L-proline + NAD(+) = 1-pyrroline-2-carboxylate + H(+) + NADH.
CC   -!- The enzyme from the bacterium Colwellia psychrerythraea is involved
CC       in trans-3-hydroxy-L-proline metabolism.
CC   -!- In contrast to EC 1.5.1.1 which shows similar activity with
CC       1-piperideine-2-carboxylate and 1-pyrroline-2-carboxylate, this
CC       enzyme is specific for the latter.
CC   -!- While the enzyme is active with both NADH and NADPH, activity is
CC       higher with NADPH.
DR   Q7CVK1, PY2CR_AGRFC;  Q73CR9, PY2CR_BACC1;  Q81HB0, PY2CR_BACCR;
DR   Q63FA5, PY2CR_BACCZ;  Q6HMS8, PY2CR_BACHK;  Q485R8, PY2CR_COLP3;
DR   A1B196, PY2CR_PARDP;  Q4KGT8, PY2CR_PSEF5;  D7A0Y0, PY2CR_STAND;
DR   Q0B9S2, PYCR1_BURCM;  A9AKH1, PYCR1_BURM1;  Q0B953, PYCR2_BURCM;
DR   A9ALD3, PYCR2_BURM1;
//