ID 1.5.3.10 DE dimethylglycine oxidase. CA (6S)-5,6,7,8-tetrahydrofolate + N,N-dimethylglycine + O2 = (6R)-5,10- CA methylene-5,6,7,8-tetrahydrofolate + H2O2 + sarcosine. CC -!- A flavoprotein (FAD). CC -!- The enzyme, characterized from the bacterium Arthrobacter CC globiformis, contains two active sites connected by a large 'reaction CC chamber'. CC -!- An imine intermediate is transferred between the sites, eliminating CC the production of toxic formaldehyde. CC -!- In the absence of folate the enzyme does form formaldehyde. CC -!- Does not oxidize sarcosine. cf. EC 1.5.8.4. DR Q9AGP8, DMGO_ARTGO ; //