ENZYME entry: EC 1.5.3.17

Accepted Name
Non-specific polyamine oxidase.
Alternative Name(s)
Polyamine oxidase.
Reaction catalysed
  • Spermine + O(2) + H(2)O <=> spermidine + 3-aminopropanal + H(2)O(2)
  • Spermidine + O(2) + H(2)O <=> putrescine + 3-aminopropanal + H(2)O(2)
  • N(1)-acetylspermine + O(2) + H(2)O <=> spermidine + 3-acetamidopropanal + H(2)O(2)
  • N(1)-acetylspermidine + O(2) + H(2)O <=> putrescine + 3-acetamidopropanal + H(2)O(2)
Cofactor(s)
FAD.
Comment(s)
  • The non-specific polyamine oxidases may differ from each other considerably.
  • The enzyme from Saccharomyces cerevisiae shows a rather broad specificity and also oxidizes N(8)-acetylspermidine.
  • The enzyme from Ascaris suum shows high activity with spermine and spermidine, but also oxidizes norspermine.
  • The enzyme from Arabidopsis thaliana shows high activity with spermidine, but also oxidizes other polyamines.
  • The specific polyamine oxidases are classified as EC 1.5.3.13, EC 1.5.3.14, EC 1.5.3.15 and EC 1.5.3.16.
  • Formerly EC 1.5.3.11, EC 1.5.3.n1, EC 1.5.3.n2 and EC 1.5.3.n4.
Cross-references
BRENDA1.5.3.17
EC2PDB1.5.3.17
ExplorEnz1.5.3.17
PRIAM enzyme-specific profiles1.5.3.17
KEGG Ligand Database for Enzyme Nomenclature1.5.3.17
IUBMB Enzyme Nomenclature1.5.3.17
IntEnz1.5.3.17
MEDLINEFind literature relating to 1.5.3.17
MetaCyc1.5.3.17
UniProtKB/Swiss-Prot
P50264, FMS1_YEAST;  Q9LYT1, PAO3_ARATH;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.5.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-