ID 1.6.3.2 DE NAD(P)H oxidase (H2O-forming). CA (1) 2 H(+) + 2 NADPH + O2 = 2 H2O + 2 NADP(+). CA (2) 2 H(+) + 2 NADH + O2 = 2 H2O + 2 NAD(+). CC -!- NADPH is a better substrate than NADH. CC -!- By removal of oxygen the enzyme is involved in aerobic tolerance in CC the thermophilic anaerobic archaeon Thermococcus profundus and in CC Giardia intestinalis, a microaerophilic single-celled parasite of the CC order Diplomonadida. DR Q5JGP4, NSR_THEKO ; //