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ENZYME entry: EC 18.104.22.168
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- 1,2-dihydro-beta-NAD(P) + H(+) + O(2) <=> beta-NAD(P)(+) + H(2)O(2)
- 1,6-dihydro-beta-NAD(P) + H(+) + O(2) <=> beta-NAD(P)(+) + H(2)O(2)
- Renalase, previously thought to be a hormone, is a flavoprotein
secreted into the blood by the kidney that oxidizes the 1,2-dihydro-
and 1,6-dihydro- isomeric forms of beta-NAD(P)H back to beta-
- These isomeric forms, generated by nonspecific reduction of beta-
NAD(P)(+) or by tautomerization of beta-NAD(P)H, are potent
inhibitors of primary metabolism dehydrogenases and pose a threat to
|PRIAM enzyme-specific profiles||22.214.171.124|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.199|
|IUBMB Enzyme Nomenclature||188.8.131.52|
|MEDLINE||Find literature relating to 184.108.40.206|
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entries corresponding to 1.6.3.-
entries corresponding to 1.6.-.-
entries corresponding to 1.-.-.-