| Accepted Name |
|---|
| NAD(P)H dehydrogenase (quinone).
|
| Alternative Name(s) |
|---|
| Azoreductase. |
| Dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate,
quinone). |
| Diaphorase. |
| DT-diaphorase. |
| Flavoprotein NAD(P)H-quinone reductase. |
| Menadione oxidoreductase. |
| Menadione reductase. |
| NAD(P)H dehydrogenase. |
| NAD(P)H menadione reductase. |
| NAD(P)H(2) dehydrogenase (quinone). |
| NAD(P)H-quinone dehydrogenase. |
| NAD(P)H-quinone oxidoreductase. |
| NAD(P)H: menadione oxidoreductase. |
| NAD(P)H:(quinone-acceptor)oxidoreductase. |
| NADH-menadione reductase. |
| Naphthoquinone reductase. |
| p-benzoquinone reductase. |
| Phylloquinone reductase. |
| Quinone reductase. |
| Reduced NAD(P)H dehydrogenase. |
| Reduced nicotinamide-adenine dinucleotide (phosphate) dehydrogenase. |
| Viologen accepting pyridine nucleotide oxidoreductase. |
| Vitamin K reductase. |
| Vitamin-K reductase. |
| Reaction catalysed |
|---|
| NAD(P)H + a quinone <=> NAD(P)(+) + a hydroquinone |
| Cofactor(s) |
|---|
| FAD.
|
| Comment(s) |
|---|
- The enzyme catalyzes a two-electron reduction and has a preference
for short-chain acceptor quinones, such as ubiquinone, benzoquinone,
juglone and duroquinone.
- The animal, but not the plant, form of the enzyme is inhibited by
dicoumarol.
- Formerly EC 1.6.99.2.
|
| Cross-references |
|---|
| BRENDA | 1.6.5.2 |
| EC2PDB | 1.6.5.2 |
| ExplorEnz | 1.6.5.2 |
| PRIAM enzyme-specific profiles | 1.6.5.2 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.6.5.2 |
| IUBMB Enzyme Nomenclature | 1.6.5.2 |
| IntEnz | 1.6.5.2 |
| MEDLINE | Find literature relating to 1.6.5.2 |
| MetaCyc | 1.6.5.2 |
| UniProtKB/Swiss-Prot |
| O53355, LPDA_MYCTU; | Q8CHK7, NQO1_CAVPO; | P15559, NQO1_HUMAN; |
| Q64669, NQO1_MOUSE; | Q5RD31, NQO1_PONAB; | P05982, NQO1_RAT; |
| Q941Z0, NQR1_ORYSJ; | Q941Y8, NQR2_ORYSJ; | Q9LK88, NQR_ARATH; |
| Q8H9D2, NQR_SOLTU; | P39315, QOR2_ECOLI; |
|