ID 1.8.1.18 DE NAD(P)H sulfur oxidoreductase (CoA-dependent). AN coenzyme A-dependent NADPH sulfur oxidoreductase. AN S(0) reductase. CA (1) hydrogen sulfide + NADP(+) = NADPH + sulfur. CA (2) hydrogen sulfide + NAD(+) = NADH + sulfur. CC -!- This enzyme, characterized from the archaeon Pyrococcus furiosus, CC is responsible for NAD(P)H-linked sulfur reduction. CC -!- The activity with NADH is about half of that with NADPH. CC -!- The reaction is dependent on CoA, although the nature of this CC dependency is not well understood. DR Q9UYU5, NSR_PYRAB ; Q8U1M0, NSR_PYRFU ; Q5JGP4, NSR_THEKO ; //