ID 1.8.1.5 DE 2-oxopropyl-CoM reductase (carboxylating). AN 2-KPCC. AN NADPH:2-(2-ketopropylthio)ethanesulfonate oxidoreductase/carboxylase. AN NADPH:2-ketopropyl-coenzyme M oxidoreductase/carboxylase. CA acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO2 + CA NADPH. CC -!- Also acts on thioethers longer in chain length on the oxo side, e.g. CC 2-oxobutyl-CoM, but this portion must be attached to CoM CC (2-sulfanylethane-1-sulfonate); no CoM analogs will substitute. CC -!- Forms component II of a four-component enzyme system (comprising CC EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268 CC (component III) and EC 1.1.1.269 (component IV)) that is involved in CC epoxyalkane carboxylation in Xanthobacter sp. strain Py2. DR Q56839, XECC_XANP2 ; //