ID   1.8.5.8
DE   eukaryotic sulfide quinone oxidoreductase.
AN   SQOR.
CA   a quinone + glutathione + H(+) + hydrogen sulfide = a quinol +
CA   S-sulfanylglutathione.
CC   -!- This eukaryotic enzyme, located at the inner mitochondrial membrane,
CC       catalyzes the first step in the metabolism of sulfide.
CC   -!- While both sulfite and glutathione have been shown to act as sulfane
CC       sulfur acceptors in vitro, it is thought that the latter acts as the
CC       main acceptor in vivo.
CC   -!- The electrons are transferred via FAD and quinones to the electron
CC       transfer chain.
CC   -!- Unlike the bacterial homolog (EC 1.8.5.4), which repeats the
CC       catalytic cycle without releasing the product, producing a
CC       polysulfide, the eukaryotic enzyme transfers the persulfide to an
CC       acceptor at the end of each catalytic cycle.
DR   Q54DK1, SQOR_DICDI ;  Q9Y6N5, SQOR_HUMAN ;  Q9R112, SQOR_MOUSE ;
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