ID 1.8.98.1 DE dihydromethanophenazine:CoB--CoM heterodisulfide reductase. AN CoB--CoM heterodisulfide reductase. AN heterodisulfide reductase. CA coenzyme B + coenzyme M + methanophenazine = coenzyme M-coenzyme B CA heterodisulfide + dihydromethanophenazine. CC -!- This enzyme, found in methanogenic archaea that belong to the CC Methanosarcinales order, regenerates CoM and CoB after the action of CC EC 2.8.4.1. CC -!- It is a membrane-bound enzyme that contains (per heterodimeric unit) CC two distinct b-type hemes and two [4Fe-4S] clusters. cf. EC 1.8.7.3, CC EC 1.8.98.5, EC 1.8.98.6 and EC 1.8.98.4. DR Q8TSV7, HDRD_METAC ; P96797, HDRD_METBF ; Q8PVW3, HDRD_METMA ; DR A0A0E3NEE1, HDRD_METTT ; Q8TSV8, HDRE_METAC ; P96796, HDRE_METBF ; DR Q8PVW4, HDRE_METMA ; A0A0E3NFS5, HDRE_METTT ; //