ID 2.1.1.113 DE Site-specific DNA-methyltransferase (cytosine-N(4)-specific). AN Modification methylase. AN N(4)-cytosine-specific DNA methylase. AN Restriction-modification system. CA S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + CA DNA N(4)-methylcytosine. CC -!- This is a large group of enzymes, the majority of which, with enzymes CC of similar site specificity listed as EC 3.1.21.3, EC 3.1.21.4 and CC EC 3.1.21.5, form so-called restriction-modification systems. CC -!- See the REBASE database for a complete list of these enzymes: CC http://rebase.neb.com/rebase/ PR PROSITE; PDOC00088; DR P0A462, MTA1_ANAVA ; P0A461, MTA1_NOSS1 ; P23941, MTB1_BACAM ; DR Q9LAI2, MTB1_BACSQ ; O68556, MTB1_BACSU ; P70986, MTB1_GEOSE ; DR P18051, MTB2_BACAM ; Q45489, MTB2_BACSU ; Q04845, MTC1_CITFR ; DR P14243, MTC9_CITFR ; P29568, MTHZ_METTF ; Q58392, MTM1_METJA ; DR Q58843, MTM2_METJA ; Q58893, MTM5_METJA ; Q58606, MTM6_METJA ; DR P14244, MTMV_MICVA ; O59647, MTMW_METWO ; P11409, MTP2_PROHU ; DR O52692, MTS1_STRCS ; O52513, MTS1_STRFI ; P14230, MTSM_SERMA ; DR P30774, MTX1_XANCC ; //