ID 2.1.1.156 DE glycine/sarcosine N-methyltransferase. AN glycine-sarcosine methyltransferase. AN glycine sarcosine N-methyltransferase. AN GMT. AN GSMT. CA glycine + 2 S-adenosyl-L-methionine = 2 H(+) + N,N-dimethylglycine + CA 2 S-adenosyl-L-homocysteine. CC -!- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece CC halophytica synthesize betaine from glycine by a three-step CC methylation process. CC -!- This is the first enzyme and it leads to the formation of either CC sarcosine or N,N-dimethylglycine, which is further methylated to CC yield betaine (N,N,N-trimethylglycine) by the action of EC 2.1.1.157. CC -!- Differs from EC 2.1.1.20, as it can further methylate the product of CC the first reaction. CC -!- Acetate, dimethylglycine and S-adenosyl-L-homocysteine can inhibit CC the reaction. DR Q9KJ20, GSDMT_ACTHA; Q83WC4, GSMT_APHHA ; Q9KJ22, GSMT_HALHR ; DR Q7U4Z8, GSMT_PARMW ; //