ID   2.1.1.157
DE   sarcosine/dimethylglycine N-methyltransferase.
AN   ApDMT.
AN   sarcosine-dimethylglycine methyltransferase.
AN   sarcosine dimethylglycine N-methyltransferase.
AN   SDMT.
CA   2 S-adenosyl-L-methionine + sarcosine = glycine betaine + 2 H(+) +
CA   2 S-adenosyl-L-homocysteine.
CC   -!- Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece
CC       halophytica synthesize betaine from glycine by a three-step
CC       methylation process.
CC   -!- The first enzyme, EC 2.1.1.156, leads to the formation of either
CC       sarcosine or N,N-dimethylglycine, which is further methylated to
CC       yield betaine (N,N,N-trimethylglycine) by the action of this enzyme.
CC   -!- Both of these enzymes can catalyze the formation of
CC       N,N-dimethylglycine from sarcosine.
CC   -!- The reactions are strongly inhibited by S-adenosyl-L-homocysteine.
DR   Q9KJ20, GSDMT_ACTHA;  Q83WC3, SDMT_APHHA ;  Q9KJ21, SDMT_HALHR ;
//