ID   2.1.1.160
DE   caffeine synthase.
AN   3N-methyltransferase.
AN   dimethylxanthine methyltransferase.
CA   (1) S-adenosyl-L-methionine + theobromine = caffeine + H(+) + S-adenosyl-
CA   L-homocysteine.
CA   (2) 1,7-dimethylxanthine + S-adenosyl-L-methionine = caffeine + H(+) +
CA   S-adenosyl-L-homocysteine.
CA   (3) 7-methylxanthine + S-adenosyl-L-methionine = H(+) + S-adenosyl-L-
CA   homocysteine + theobromine.
CC   -!- Paraxanthine is the best substrate for this enzyme but the
CC       paraxanthine pathway is considered to be a minor pathway for caffeine
CC       biosynthesis.
DR   A0A6C0WW38, CKCS_CAMSB ;  Q8H0D2, DXMT1_COFAR;  A4GE70, DXMT1_COFCA;
DR   Q8H0D3, DXMT2_COFAR;  A0A0S2PMA8, TCS1D_CAMTA;  A0A0S2PM92, TCS1F_CAMCR;
DR   Q9FZN8, TCS1_CAMSI ;  Q68CM3, TCS2_CAMSI ;  A0A0S2PM82, TCS3_CAMSI ;
//