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ENZYME entry: EC 184.108.40.206
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|27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase.
|S-adenosyl-L-methionine + guanosine(2922) in 27S pre-rRNA <=> S-adenosyl-L-homocysteine + 2'-O-methylguanosine(2922) in 27S pre-rRNA|
- Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that
catalyzes the formation of 2'-O-methylguanosine(2922), a universally
conserved position of the catalytic center of the ribosome that is
essential for translation.
- 2'-O-methylguanosine(2922) is formed at a later stage of the
processing, during the maturation of of the 27S pre-rRNA.
- In absence of snR52, Spb1p can also catalyze the formation of
|PRIAM enzyme-specific profiles||220.127.116.11|
|KEGG Ligand Database for Enzyme Nomenclature||18.104.22.168|
|IUBMB Enzyme Nomenclature||22.214.171.124|
|MEDLINE||Find literature relating to 126.96.36.199|
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