ID   2.1.1.179
DE   16S rRNA (guanine(1405)-N(7))-methyltransferase.
AN   sisomicin-gentamicin methyltransferase.
CA   guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine = N(7)-
CA   methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine.
CC   -!- The enzyme from the antibiotic-producing bacterium Micromonospora
CC       zionensis specifically methylates guanine(1405) at N(7) in 16S rRNA,
CC       thereby rendering the ribosome resistant to 4,6-disubstituted
CC       deoxystreptamine aminoglycosides, which include gentamicins and
CC       kanamycins.
DR   Q08325, FMRO_MICOL ;  P24618, GRM_MICEC  ;  P24619, GRM_MICRO  ;
DR   Q2J7L5, KRM_FRACC  ;  Q76G15, RMTB_SERMA ;  Q33DX5, RMTC_PROMI ;
DR   Q7M0R2, SGM_MICZI  ;
//