To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 2.1.1.180

Accepted Name
16S rRNA (adenine(1408)-N(1))-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + adenine(1408) in 16S rRNA <=> S-adenosyl-L-homocysteine + N(1)-methyladenine(1408) in 16S rRNA
Comment(s)
The enzyme provides a panaminoglycoside-resistant nature through interference with the binding of aminoglycosides toward the A site of 16S rRNA through N(1)-methylation at position adenine(1408).
Cross-references
BRENDA2.1.1.180
EC2PDB2.1.1.180
ExplorEnz2.1.1.180
PRIAM enzyme-specific profiles2.1.1.180
KEGG Ligand Database for Enzyme Nomenclature2.1.1.180
IUBMB Enzyme Nomenclature2.1.1.180
IntEnz2.1.1.180
MEDLINEFind literature relating to 2.1.1.180
MetaCyc2.1.1.180
UniProtKB/Swiss-Prot
Q2MEY3, KAMB_STRHI;  P25920, KAMB_STRSD;  A8C927, NPMA_ECOLX;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-