ID 2.1.1.203 DE tRNA (cytosine(34)-C(5))-methyltransferase. CA cytidine(34) in tRNA precursor + S-adenosyl-L-methionine = CA 5-methylcytidine(34) in tRNA precursor + H(+) + S-adenosyl-L- CA homocysteine. CC -!- The human enzyme is specific for C(5)-methylation of cytosine(34) in CC tRNA precursors. CC -!- The intron in the human pre-tRNA(Leu)(CAA) is indispensable for the CC C(5)-methylation of cytosine in the first position of the anticodon. CC -!- It is not able to form 5-methylcytosine at positions 48 and 49 of CC human and yeast tRNA precursors. CC -!- Formerly EC 2.1.1.29. DR Q5ZLV4, NSUN2_CHICK; Q9W4M9, NSUN2_DROME; Q08J23, NSUN2_HUMAN; DR Q1HFZ0, NSUN2_MOUSE; Q4V7N2, NSUN2_XENLA; Q28E61, NSUN2_XENTR; DR Q9HGQ2, TRM4A_SCHPO; //