ID   2.1.1.207
DE   tRNA (cytidine(34)-2'-O)-methyltransferase.
AN   tRNA (cytidine(34)/5-carboxymethylaminomethyluridine(34)-2'-O)-
AN   methyltransferase.
AN   tRNA methyltransferase L.
CA   (1) cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-
CA   methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine.
CA   (2) 5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-
CA   methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in
CA   tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine.
CC   -!- The enzyme from Escherichia coli catalyzes the 2'-O-methylation of
CC       cytidine or 5-carboxymethylaminomethyluridine at the wobble position
CC       at nucleotide 34 in tRNA(Leu)CmAA and tRNA(Leu)cmnm(5)UmAA.
CC   -!- The enzyme is selective for the two tRNA(Leu) isoacceptors and only
CC       methylates these when they present the correct anticodon loop
CC       sequence and modification pattern.
CC   -!- Specifically, YibK requires a pyrimidine nucleoside at position 34,
CC       it has a clear preference for an adenosine at position 35, and it
CC       fails to methylate without prior addition of the N(6)-(isopentenyl)-
CC       2-methylthioadenosine modification at position 37.
DR   A1WBM9, TRML_ACISJ ;  A0KEQ6, TRML_AERHH ;  O31590, TRML_BACSU ;
DR   B2IBT9, TRML_BEII9 ;  A0KAS4, TRML_BURCH ;  Q0BBL1, TRML_BURCM ;
DR   A3NR15, TRML_BURP0 ;  P0AGJ8, TRML_ECOL6 ;  P0AGJ7, TRML_ECOLI ;
DR   P32813, TRML_GEOSE ;  P44868, TRML_HAEIN ;  Q042B4, TRML_LACGA ;
DR   A2RKW7, TRML_LACLM ;  P69001, TRML_LISIN ;  Q721N0, TRML_LISMF ;
DR   C6X9I5, TRML_METGS ;  P47588, TRML_MYCGE ;  P75257, TRML_MYCPN ;
DR   C7BSD3, TRML_PHOAA ;  Q12E50, TRML_POLSJ ;  Q21LN7, TRML_SACD2 ;
DR   B8CHC9, TRML_SHEPW ;  D7A3L6, TRML_STAND ;  Q48V41, TRML_STRPM ;
DR   P74516, TRML_SYNY3 ;  Q74Y93, TRML_YERPE ;
//