ID   2.1.1.226
DE   23S rRNA (cytidine(1920)-2'-O)-methyltransferase.
CA   cytidine(1920) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-
CA   methylcytidine(1920) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine.
CC   -!- The bifunctional enzyme from Mycobacterium tuberculosis 2'-O-
CC       methylates cytidine(1920) in helix 69 of 23S rRNA and cytidine(1409)
CC       in helix 44 of 16S rRNA (cf. EC 2.1.1.227).
CC   -!- These methylations result in increased susceptibility to the
CC       antibiotics capreomycin and viomycin.
DR   A0A0H3PEK7, TLYA_CAMJJ ;  P9WJ62, TLYA_MYCTO ;  P9WJ63, TLYA_MYCTU ;
//