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ENZYME

ENZYME entry: EC 2.1.1.258

Accepted Name
5-methyltetrahydrofolate:corrinoid/iron-sulfur protein Co-methyltransferase
Reaction catalysed
(6S)-5,6,7,8-tetrahydrofolate + methyl-Co(III)-[corrinoid Fe-S protein] <=> (6S)-5-methyl-5,6,7,8-tetrahydrofolate + Co(I)-[corrinoid Fe-S protein] + H(+)
Comment(s)
  • Catalyzes the transfer of a methyl group from the N(5) group of methyltetrahydrofolate to the 5-methoxybenzimidazolylcobamide cofactor of a corrinoid/Fe-S protein.
  • Involved, together with EC 1.2.7.4 and EC 2.3.1.169, in the reductive acetyl coenzyme A (Wood-Ljungdahl) pathway of autotrophic carbon fixation in various bacteria and archaea.
Cross-references
BRENDA2.1.1.258
EC2PDB2.1.1.258
ExplorEnz2.1.1.258
PRIAM enzyme-specific profiles2.1.1.258
KEGG Ligand Database for Enzyme Nomenclature2.1.1.258
IUBMB Enzyme Nomenclature2.1.1.258
IntEnz2.1.1.258
MEDLINEFind literature relating to 2.1.1.258
MetaCyc2.1.1.258
Rhea expert-curated reactions2.1.1.258
UniProtKB/Swiss-Prot
Q46389, ACSE_MOOTH

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