ID   2.1.1.272
DE   cobalt-factor III methyltransferase.
CA   AH2 + Co(II)-factor III + S-adenosyl-L-methionine = A + Co-precorrin-4 +
CA   S-adenosyl-L-homocysteine.
CC   -!- Isolated from the bacterium Bacillus megaterium.
CC   -!- The enzyme, which participates in the anaerobic (early cobalt
CC       insertion) pathway of adenosylcobalamin biosynthesis, catalyzes a
CC       crucial reaction where the tetrapyrrole ring contracts as a result of
CC       methylation of C-17.
CC   -!- Contains a [4Fe-4S] cluster.
CC   -!- It can also convert cobalt-precorrin-3 to cobalt-precorrin-4.
CC   -!- The reductant may be thioredoxin.
CC   -!- See EC 2.1.1.131 for the corresponding enzyme that participates in
CC       the aerobic cobalamin biosynthesis pathway.
DR   O87689, CBIH_PRIMG ;
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