ENZYME entry: EC 2.1.1.286

Accepted Name
25S rRNA (adenine(2142)-N(1))-methyltransferase.
Alternative Name(s)
25S rRNA m(1)A(2142) methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + adenine(2142) in 25S rRNA <=> S-adenosyl-L-homocysteine + N(1)-methyladenine(2142) in 25S rRNA
Comment(s)
In the yeast Saccharomyces cerevisiae this methylation is important for resistance toward hydrogen peroxide and the antibiotic anisomycin.
Cross-references
BRENDA2.1.1.286
EC2PDB2.1.1.286
ExplorEnz2.1.1.286
PRIAM enzyme-specific profiles2.1.1.286
KEGG Ligand Database for Enzyme Nomenclature2.1.1.286
IUBMB Enzyme Nomenclature2.1.1.286
IntEnz2.1.1.286
MEDLINEFind literature relating to 2.1.1.286
MetaCyc2.1.1.286
UniProtKB/Swiss-Prot
P38278, BMT2_YEAST

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